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Creators/Authors contains: "Brown, Alexander"

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  1. Despite a documented push to expand nuclear energy in the U.S., the status quo of indefinite in-situ nuclear waste storage is uncertain and increasingly threatened by climate and coastal hazards. Findings from Humboldt Bay, California, one of the nation’s most vulnerable nuclear storage sites, informed recommendations for managing emergent climate and coastal hazards. The existing legislative framework was not designed to address climate and nuclear waste interactions, but more effective oversight leveraging existing federal, state, local, and Tribal government authorities could adapt spent nuclear fuel management to a climate-changed world. More effective oversight requires updated regulations and site-specific risk assessments as well as enhanced coordination across jurisdictions, disciplines, and publics to increase legitimacy, trust, accountability, and creativity in light of failed solutions to a multi-decadal issue. 
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  2. Alcoholysis of (C5H4SiMe)3Ln results in bimetallic complexes with unexpected decreases in Ln⋯Ln distances as bridging alkoxides become bulkier. These complexes were characterized by DOSY NMR, CV, DPV, and a LaIIspecies was observed by EPR. 
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  3. Abstract The characterization of young planets (<300 Myr) is pivotal for understanding planet formation and evolution. We present the 3–5μm transmission spectrum of the 17 Myr, Jupiter-size (R∼10R) planet, HIP 67522b, observed with JWST NIRSpec/G395H. To check for spot contamination, we obtain a simultaneousg-band transit with the Southern Astrophysical Research Telescope. The spectrum exhibits absorption features 30%–50% deeper than the overall depth, far larger than expected from an equivalent mature planet, and suggests that HIP 67522b’s mass is <20Mirrespective of cloud cover and stellar contamination. A Bayesian retrieval analysis returns a mass constraint of 13.8 ± 1.0M. This challenges the previous classification of HIP 67522b as a hot Jupiter and instead, positions it as a precursor to the more common sub-Neptunes. With a density of <0.10 g cm−3, HIP 67522 b is one of the lowest-density planets known. We find strong absorption from H2O and CO2(≥7σ), a modest detection of CO (3.5σ), and weak detections of H2S and SO2(≃2σ). Comparisons with radiative-convective equilibrium models suggest supersolar atmospheric metallicities and solar-to-subsolar C/O ratios, with photochemistry further constraining the inferred atmospheric metallicity to 3 × 10 solar due to the amplitude of the SO2feature. These results point to the formation of HIP 67522b beyond the water snowline, where its envelope was polluted by icy pebbles and planetesimals. The planet is likely experiencing substantial mass loss (0.01–0.03MMyr−1), sufficient for envelope destruction within a gigayear. This highlights the dramatic evolution occurring within the first 100 Myr of its existence. 
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    Free, publicly-accessible full text available December 1, 2025
  4. Abstract Alternative end joining (alt-EJ) mechanisms, such as polymerase theta-mediated end joining, are increasingly recognized as important contributors to inaccurate double-strand break repair. We previously proposed an alt-EJ model whereby short DNA repeats near a double-strand break anneal to form secondary structures that prime limited DNA synthesis. The nascent DNA then pairs with microhomologous sequences on the other break end. This synthesis-dependent microhomology-mediated end joining (SD-MMEJ) explains many of the alt-EJ repair products recovered following I-SceI nuclease cutting in Drosophila. However, sequence-specific factors that influence SD-MMEJ repair remain to be fully characterized. Here, we expand the utility of the SD-MMEJ model through computational analysis of repair products at Cas9-induced double-strand breaks for 1100 different sequence contexts. We find evidence at single nucleotide resolution for sequence characteristics that drive successful SD-MMEJ repair. These include optimal primer repeat length, distance of repeats from the break, flexibility of DNA sequence between primer repeats, and positioning of microhomology templates relative to preferred primer repeats. In addition, we show that DNA polymerase theta is necessary for most SD-MMEJ repair at Cas9 breaks. The analysis described here includes a computational pipeline that can be utilized to characterize preferred mechanisms of alt-EJ repair in any sequence context. 
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  5. Abstract We present light curves and flares from a 7 day, multiwavelength observational campaign of AU Mic, a young and active dM1e star with exoplanets and a debris disk. We report on 73 unique flares between the X-ray to optical data. We use high-time-resolution near-UV (NUV) photometry and soft X-ray (SXR) data from the X-ray Multi-Mirror Mission to study the empirical Neupert effect, which correlates the gradual and impulsive phase flaring emissions. We find that 65% (30 of 46) flares do not follow the Neupert effect, which is 3 times more excursions than seen in solar flares, and propose a four-part Neupert effect classification (Neupert, quasi-Neupert, non-Neupert types I and II) to explain the multiwavelength responses. While the SXR emission generally lags behind the NUV as expected from the chromospheric evaporation flare models, the Neupert effect is more prevalent in larger, more impulsive flares. Preliminary flaring rate analysis with X-ray andU-band data suggests that previously estimated energy ratios hold for a collection of flares observed over the same time period, but not necessarily for an individual, multiwavelength flare. These results imply that one model cannot explain all stellar flares and care should be taken when extrapolating between wavelength regimes. Future work will expand wavelength coverage using radio data to constrain the nonthermal empirical and theoretical Neupert effects to better refine models and bridge the gap between stellar and solar flare physics. 
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  6. Direct laser scribing of molybdenum dioxide is enabled on soft elastomers to build Janus wearables and reshapable devices. 
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  7. null (Ed.)
  8. Abstract The mergers of binary compact objects such as neutron stars and black holes are of central interest to several areas of astrophysics, including as the progenitors of gamma-ray bursts (GRBs)1, sources of high-frequency gravitational waves (GWs)2and likely production sites for heavy-element nucleosynthesis by means of rapid neutron capture (ther-process)3. Here we present observations of the exceptionally bright GRB 230307A. We show that GRB 230307A belongs to the class of long-duration GRBs associated with compact object mergers4–6and contains a kilonova similar to AT2017gfo, associated with the GW merger GW170817 (refs. 7–12). We obtained James Webb Space Telescope (JWST) mid-infrared imaging and spectroscopy 29 and 61 days after the burst. The spectroscopy shows an emission line at 2.15 microns, which we interpret as tellurium (atomic massA = 130) and a very red source, emitting most of its light in the mid-infrared owing to the production of lanthanides. These observations demonstrate that nucleosynthesis in GRBs can creater-process elements across a broad atomic mass range and play a central role in heavy-element nucleosynthesis across the Universe. 
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